Dr. Sheraz R. Markar

General Surgery

Esophageal and; Gastric Surgery, Department of Oesophago-Gastric Surgery, Oxford University Hospital NHS Trust, Department of Molecular Medicine and; Surgery, Karolinska Institute, Sweden

United Kingdom

Biography Publications Featured in

Biography

Experienced clinical researcher with strong interest in clinical trial design and implementation. Research and clinical interest in benign and malignant oesophageal and gastric disease.

Publications

Selected publications from PubMed

The Impact of Anastomotic Leak After Esophagectomy on Long-term Survival in the Modern Era of Management (ALES Study): A Multicenter Cohort Study.

Giorgi L, Guidozzi N, Salem R, Chou WK, Vanstraelen S, Gielen H, Moons J, Nafteux P, Lammes FE, Ruurda JP, van Hillegersberg R, Todesco A, D'Journo XB, Collizzolli A, Ajazi B, Giacopuzzi S, Bencivenga M, Alhayo S, Seabourne E, Griffiths EA, Abu Hejleh A, Schiffmann LM, Bruns CJ, Garbarino GM, Pansa A, Basato S, Bacoeur-Ouzillou O, Gronnier C, Henckens SPG, Gisbertz SS, Ahmed R, Loganathan N, Elliott JA, Cole K, Ibrahim Y, Anand C, Pucher PH, Skogar M, Hedberg J, Bonnin E, Veziant J, Piessen G, Carresi A, Puccetti F, Battaglia S, Rosati R, Murad F, Klevebro F, Nilsson M, Nieuwenhuijzen GAP, van de Sanden L, Luyer M, Alfieri R, Castoro C, van Berge Henegouwen MI, Markar SR

Ann Surg. 2026 Sep 3 doi: 10.1097/SLA.0000000000007190.

Development and Reliability of a Competency Assessment Tool for Magnetic Sphincter Augmentation of the Esophagus (MSA CAT) as Part of a Video-based Surgical Quality Assurance Program for the GOLF Trial.

Menon N, Goldsmith P, Owen R, Paine H, Bencivenga M, Bonavina L, Gossage J, Gutschow CA, Mittal S, Leers JM, Lipham J, Schoppmann SF, Ahmed A, Ayazi S, Blencowe NS, Markar SR

Ann Surg. 2026 Aug 6 doi: 10.1097/SLA.0000000000007160.

The Prognostic Impact of Lymph Node Yield Upon Survival in Esophageal Cancer Broken Down by Neoadjuvant Strategy: A Multicenter European Cohort Study.

Guidozzi N, Chou WK, Giorgi L, Salem R, Vanstraelen S, Gielen H, Moons J, Nafteux P, Lammes FE, Ruurda JP, van Hillegersberg R, Todesco A, D'Journo XB, Collizzolli A, Ajazi B, Giacopuzzi S, Bencivenga M, Alhayo S, Seabourne E, Griffiths EA, Abu Hejleh A, Schiffmann LM, Bruns CJ, Garbarino GM, Pansa A, Basato S, Bacoeur-Ouzillou O, Gronnier C, Henckens SPG, Gisbertz SS, Ahmed R, Loganathan N, Elliott JA, Cole K, Ibrahim Y, Anand C, Pucher PH, Skogar M, Hedberg J, Bonnin E, Veziant J, Piessen G, Carresi A, Battaglia S, Puccetti F, Rosati R, Murad F, Klevebro F, Nilsson M, Nieuwenhuijzen GAP, van de Sanden L, Luyer MDP, Alfieri R, Castoro C, van Berge Henegouwen MI, Markar SR

Ann Surg. 2026 Jul 31 doi: 10.1097/SLA.0000000000007164.

FLOT vs CROSS Among Patients With Pathological Complete Response in Esophageal Adenocarcinoma.

Alhayo S, Chou WK, Giorgi L, Guidozzi N, Griffiths EA, Markar SR, ALES Study Collaborative Group, Seabourne E, Salem R, Vanstraelen S, Gielen H, Moons J, Nafteux P, Lammes FE, Ruurda JP, van Hillegersberg R, Todesco A, D'Journo XB, Collizzolli A, Ajazi B, Giacopuzzi S, Bencivenga M, Abu Hejleh A, Schiffmann LM, Bruns CJ, Garbarino GM, Pansa A, Basato S, Bacoeur-Ouzillou O, Gronnier C, Henckens SPG, Gisbertz SS, Ahmed R, Loganathan N, Elliott JA, Cole K, Ibrahim Y, Anand C, Pucher PH, Skogar M, Hedberg J, Bonnin E, Veziant J, Piessen G, Carresi A, Battaglia S, Rosati R, Murad F, Klevebro F, Nilsson M, Nieuwenhuijzen GAP, van de Sanden L, Luyer MDP, Alfieri R, Castoro C, van Berge Henegouwen MI

JAMA Surg. 2026 Sep 1;161(9):917-925 doi: 10.1001/jamasurg.2026.2703.

Pre- and Post-Treatment Predictive Models of Peritoneal Recurrence After Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel-Chemotherapy and Surgery: An International Study.

Lee MM, Wong DJ, Hall K, Duong CP, Watson DI, Donohoe CL, Bright T, Aly A, Chan K, Chan DL, Merrett N, Gananadha S, Lam YH, Kanhere H, Smithers BM, Bozin M, Read M, Mori K, Johnson MA, Wong E, Martin SA, Ooi G, Al-Habbal Y, Liew CH, Bohmer R, Daruwalla J, Ballal M, Ranjan R, MacCormick AD, Pattison S, Evennett N, Robertson J, Tan J, Gordon A, Bann S, Samarasam I, Gurunathan R, So J, Yeung J, Ferri L, Griffiths EA, Phillips AW, Markar SR, Chan D, Murphy T, Reynolds J, Nilsson M, Piessen G, Wijnhoven B, van Hillegersberg R, van Berge Henegouwen MI, Lombardi PM, Clemons NJ, Allan Z, Hamilton AJ, Liu DS, SPACE-FLOT Investigators

JCO Precis Oncol. 2026 Jul;10(7):e2501145 doi: 10.1200/PO-25-01145.

Featured in

15 min

Assurance of Surgical Quality; from the Trial to Clinical Practice

The assurance of surgical quality within randomised controlled trials has increasingly become a focus in the design and implementation stages of complex surgical trials. We have previously shown the importance of surgical quality assurance in reducing mortality and variation in lymph node harvest within surgical randomised controlled trials for oesophageal and gastric cancer. Typically as surgeons we measure harm from surgical interventions, as we introduce more technology to surgery the next step is to focus on intraoperative analysis to reduce patient harm before it occurs. Through ongoing development of observed clinical human reliability analysis (OCHRA) in several surgical specialties, we are developing the tools to quantify surgical performance. This in turn can reduce patient harm in departing from the tightly controlled randomised controlled trial environment to real life clinical practice. In this presentation we will explore the importance of surgical quality assurance, OCHRA, and future steps in improving the transition from clinical trials to clinical practice.

Published

Oct 2021

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