Genetic predisposition to colorectal cancer
Current genetic knowledge has clarified several questions in modern medicine. Gene mutations or the combination of alleles increase the susceptibility to certain pathologies. This fact has a clinical translation into familial syndromes and increased risk of cancer. This lecture focuses on the genetic predisposition to colorectal cancer. Sergi Castellví will go from the basics (DNA and human genome) to their current association with one of the most frequent neoplasms, colorectal cancer. The latest available data will be reviewed as well as ongoing studies to discover new associations that make more precise counseling, follow up and tailored treatments possible.
