Dr. Patricia Sylla has been a leader in developing minimally invasive approaches to the surgical treatment of colon and rectal cancer. She joined Mount Sinai from Massachusetts General Hospital, where she practiced for seven years within the Division of General and Gastrointestinal Surgery and was an Assistant Professor of Surgery at Harvard Medical School. While there, Dr. Sylla developed a research and clinical program using Natural Orifice Transluminal Endoscopic Surgery.
Selected publications from PubMed
Safety and Performance of the Colovac Anastomosis Protection Device. A Pooled Analysis of Prospective Studies Compared With Diverting Loop Ileostomy (SAFE-2025).
Sylla P, Lam K, Komen N, Tuech JJ, Spinelli A, Martz J, Rhee R, Marcet J, Cadière GB, Rouanet P, Karachun A, Denost Q, Sametdinov N, D'Hoore A, Lee S, Lefèvre JH
Ann Surg. 2026 Sep 2 doi: 10.1097/SLA.0000000000007171.
Systematic review and meta-analysis on key controversies in the management of diverticular disease: a multi-society collaboration.
Huo B, Dourado J, Khaldi MA, Ntaga I, Broderick J, Shehata D, Calabrese E, Lingam G, de Sadeleer A, Barbera E, Reinke C, Carrano F, Breukink S, Kaiser A, Marafini I, Biffl W, Catena F, Frizelle F, Doulias T, Tursi A, Kimble J, Buchenholz N, Walls S, Yao X, Guyatt G, Yiasemidou M, Heuvelings D, Garfinkle R, Abou-Khalil M, Slater BJ, Antoniou SA, Bouvy N, Sylla P, Francis N, Boutros M
Surg Endosc. 2026 Sep 1 doi: 10.1007/s00464-026-13297-0.
Sustainability in surgery: insights from the 2024 SAGES Annual Meeting.
Wignakumar A, Dourado J, Emile SH, Fiore JF Jr, Sylla P, Wexner SD, Linkeshwaran L, Boutros M, Monton O
Surg Endosc. 2026 Aug 10 doi: 10.1007/s00464-026-13181-x.
Long-term Results of the North American Phase II Transanal Total Mesorectal Excision Multicenter Trial for Rectal Cancer.
Donovan KF, Carmichael H, Chadi S, Ricardo A, Bonaccorso A, Tomada EP, Sands D, Marks J, Maykel J, Alavi K, Zaghiyan K, Whiteford M, McLemore EC, Shawki SF, Steele S, Pigazzi A, Albert M, DeBeche-Adams T, Avery L, Wexner S, Sylla P
Ann Surg. 2026 Aug 1;284(2):236-243 doi: 10.1097/SLA.0000000000007044.
Clinical spotlight review: best practices for the management of colorectal cancer in the emergency and acute care setting.
Tejedor P, Pastor C, Caycedo-Marulanda A, Whiteford M, McLemore EC, Sylla P, Boutros M, Alkhamesi NA, SAGES Colorectal Committee, Acute Care Surgery Committee
Surg Endosc. 2026 Jul;40(7):5459-5467 doi: 10.1007/s00464-026-12880-9.
After two decades, the robotic revolution is at a tipping point. It's moving "Beyond the Early Adopters" to redefine surgical standards for all. But how do we bridge the gap from an "elite" technology to an "essential" tool for every hospital? This premiere episode explores the evolution of robotic surgery, from its pioneering days to the next-generation platforms built for widespread adoption, flexibility, and universal access.
With Rob Surgical
Published
Nov 2025
The world of surgery is undergoing a major transformation with the advent of Laparoscopy 4.0, where advanced technologies such as robotics and AI are reshaping the landscape of medical practice. This new era is characterized by innovations that not only empower surgeons with enhanced capabilities but also improve the efficiency of the entire operating room team. In this webinar, we will explore how technologies like robotic-assisted surgery are making a significant impact on laparoscopic procedures, offering surgeons greater precision and control.
With Moon Surgical
Published
Apr 2025
Dr. John D. Mellinger, Dr. Patricia Sylla,Dr. Steven D. Wexner, Dr. John D. Mellinger, Dr. Liane Feldman, Dr. Alia Qureshi, Dr. Shaneeta Johnson, Dr. Aurora Pryor present multiple solutions to address DEI within Surgical Organizations.
With Johnson & Johnson MedTech
Published
Feb 2023
Anastomotic leaks are among the most dreaded complications in surgical practice. Leaks in colorectal surgery operations are more common when a distal colorectal, coloanal, or ileoanal anastomosis is fashioned. The high financial, medical, and functional costs which ensue following anastomotic leaks have been the impetus for continued research into methods to reduce the incidence of or ideally prevent leaks. The faculty of internationally acclaimed experts in this program address the gamut of leaks from incidence and cost to avoidance, diagnosis and treatment.
With Johnson & Johnson MedTech
Published
Feb 2022
Dr. Sylla comments on the video of a colorectal anastomosis procedure. In particular, she comments on the rectosigmoid resection of a female patient. However, the sigmoid dissection is not shown. Thus, the video shows how to prepare for the anastomosis, from different points of view (laparoscopic, of the operation room…) During the video, the doctor gives some insights, recommendations and advice for every step.
With Johnson & Johnson MedTech
Published
Feb 2022
Fluorescence Imaging event presented by Dr. Manish Chand and Dr. Steven Wexner.
With Karl Storz
Published
Jul 2021
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