
Dr. Marylise Boutros, MD, FACS, FRCSC is a Staff Colorectal Surgeon at the Cleveland Clinic Florida and the Regional Director of Research for the Digestive Disease Institute. Previously, Dr. Boutros was a Colorectal Surgeon at the Jewish General Hospital (2012- 2023) in Montreal, a Professor of Surgery at McGill University, and Colorectal Surgery Program Director at the McGill Faculty of Medicine. Dr Boutros completed her General Surgery residency at McGill University and her Colorectal Surgery residency at Cleveland Clinic Florida.
Dr Boutros’s clinical interests are advanced minimally invasive approaches to benign and malignant colorectal and anorectal diseases. She treats colon and rectal cancer, inflammatory bowel disease, diverticular disease, fecal incontinence and all anorectal disorders. Dr Boutros is an internationally renowned expert in the prevention and treatment of Low Anterior Resection Syndrome (LARS) following rectal cancer treatment.
Dr Boutros has created and led a successful Colorectal Surgery Research Outcomes Lab that focuses on improving patient recovery, long-term outcomes and health-related quality of life following colorectal surgery. Thus far, Dr Boutros has successfully led and completed 6 investigator-initiated randomized-controlled trials, and five cohort studies, involving multiple sites and international participation.
Dr. Boutros has a stellar track record of scientific contribution to the field, having published 120 peer-reviewed publications (65 senior authors) in high-impact surgical journals, >250 conference abstracts, and 14 book chapters in leading surgical textbooks (4,909 citations, H-index: 36), since the start of her academic career. To support her research, Dr. Boutros has been highly successful in obtaining peer-reviewed operating research grants as a principal investigator (>$1.2 mil) over the last 9 years from various surgical and cancer societies, as well as federal and provincial agencies. She has also received consecutive salary awards to support her work since 2013.
Dr Boutros is very active and prolific in her participation in the advancement of the field of colorectal surgery. She has held key leadership roles in several surgical societies such as the Society of American Gastrointestinal and Endoscopic Surgeons, the American Society of Colon and Rectal Surgeons, the Canadian Society of Colon and Rectal Surgeons and the Canadian Association of General Surgeons.
Selected publications from PubMed
Intraoperative Systemic Chemotherapy in Stage II-III Appendiceal Adenocarcinoma: A National Cancer Database Analysis.
Perets M, Kahana N, Freund MR, Horesh N, Al Khaldi M, Bayat Z, Boutros M, Emile SH
J Gastrointest Cancer. 2026 Sep 3;57(1) pii: 210. doi: 10.1007/s12029-026-01587-8.
Systematic review and meta-analysis on key controversies in the management of diverticular disease: a multi-society collaboration.
Huo B, Dourado J, Khaldi MA, Ntaga I, Broderick J, Shehata D, Calabrese E, Lingam G, de Sadeleer A, Barbera E, Reinke C, Carrano F, Breukink S, Kaiser A, Marafini I, Biffl W, Catena F, Frizelle F, Doulias T, Tursi A, Kimble J, Buchenholz N, Walls S, Yao X, Guyatt G, Yiasemidou M, Heuvelings D, Garfinkle R, Abou-Khalil M, Slater BJ, Antoniou SA, Bouvy N, Sylla P, Francis N, Boutros M
Surg Endosc. 2026 Sep 1 doi: 10.1007/s00464-026-13297-0.
Reply.
Moon J, Boutros M
Dis Colon Rectum. 2026 Sep 1;69(9):2352 doi: 10.1097/DCR.0000000000004297.
How Does the Surgical Margin Status Affect the Association Between Mesorectal Excision Quality and Overall Survival in Patients With Locally Advanced Rectal Cancer? A Contemporary Analysis From the NCDB.
Emile SH, Horesh N, Al Khaldi M, Bayat Z, Kahana N, Perets M, Maron D, Boutros M
J Surg Oncol. 2026 Aug 31 doi: 10.1002/jso.70378.
A propensity score matched ACS-NSQIP database analysis of primary anastomosis with or without diversion for acute perforated diverticulitis.
Kahana N, Emile SH, Perets M, Al Khaldi M, Bayat Z, Boaz E, Horesh N, Boutros M
J Gastrointest Surg. 2026 Oct;30(10):102548 doi: 10.1016/j.gassur.2026.102548.

Anastomotic leaks are among the most devastating complications in all forms of gastrointestinal surgery. The rates and adverse sequelae of anastomotic leaks are most common and potentially of the greatest detrimental impact at the two ends of the intestinal tract - the esophagus and the rectum. This program is the first one in a four-part series delving into every facet of anastomotic leaks in colorectal surgery practice. Bringing together 5 globally renowned experts, it addresses the incidence, financial, functional, and oncological costs of leaks. Dr. Antonio M. de Lacy, the founder of the AIS Channel, will demonstrate laparoscopic leak management. The program will conclude with a lively globally interactive panel discussion. Designed for every surgeon and surgical trainee involved in colorectal anastomosis, this program offers invaluable insights.
With Medtronic
Published
Apr 2024

Welcome & Introduction – Dr. Steven D. Wexner (USA) Combination therapy – Treat the intestinal mucosa to treat the fistula - Dr. Sara El Ouali (UAE/USA) Who is a candidate for stem cells? - Dr. Julián Panés (Spain) Practical tips for optimizing the success of stem cell therapy - Dr. Louis J. Cohen (USA) Patient-reported outcomes in fistula surgery - Dr. Marylise Boutros (Canada) The results of stem cells for anal fistulas – Dr. Giovanna da Silva (USA) Video stem cells for anal fistulas - Dr. Phillip Fleshner (USA) Panel discussion & Closing Remarks - All faculty moderated by Dr. Steven D. Wexner (USA) *Supported by an educational grant from Takeda Pharmaceuticals U.S.A.
With Takeda
Published
Jul 2023
Help your network discover Dr. Marylise Boutros's clinical expertise.