

Surgical Oncology
MD, FACS, Professor of Surgery, Chief of Surgical Oncology, Eastern Virginia Medical School, USA
Dr. Marybeth Hughes, MD FACS joins EVMS Surgery as Chief of Surgical Oncology. Previously, she served as a Surgical Oncologist at The Surgery Branch and the Thoracic and Gastrointestinal Oncology Branch Center for Cancer Research at the National Cancer Institute, National Institutes of Health (NIH) in Bethesda Maryland. There she also was Director for the Surgical Oncology Research Fellowship Program.
Dr. Hughes is certified by the American Board of Surgery, Fellow of the American College of Surgeons, Advanced Trauma Life Support Instructor and DaVinci Robotic Console Surgeon. She often serves as a reviewer for the Journal of Surgical Oncology, Endocrine-Related Cancer, World Journal of Surgery, Surgery, Annals of Surgery, Clinical Endocrinology, The American Journal of the Medical Sciences, The Cancer Journal: The Journal of Principles & Practice of Oncology.
Dr. Hughes has served as principal investigator and associate investigator for various clinical trials at NIH on cancer related protocols. Her work has been published in numerous journals and books on surgical oncology topics most notably related to neuroendocrine tumors, melanoma liver metastases, pancreatic cancer, adenocarcinoma of the appendix, colorectal cancers, and breast cancer. Dr. Hughes is a national and international presenter on surgical oncology topics and continues to teach and mentor medical students, residents and fellows in surgical oncology. While at the NIH, Dr. Hughes re-developed the curriculum, for the Surgical Oncology Research Fellowship Program and taught Advanced Trauma Life Support for the Department of Defense.
Selected publications from PubMed
Prognostic Factors for Patients Under 45 Undergoing Surgery for Colorectal Liver Metastases: A SEER Population-Based Study.
Grob G, Fang F, Karpov M, Feliberti E, Hughes M, Burke R, Lo W
J Surg Oncol. 2026 Sep;134(3):322-329 doi: 10.1002/jso.70300.
Pancreaticojejunostomy with duct-to-mucosa versus invagination techniques: a propensity-score matching analysis based on pancreatic duct size and gland texture.
Gaitanidis A, Lo WM, Burke RA, Feliberti EC, Rallos EP, May AM, Akari AN, Hughes MS, Fagenholz PJ
Am J Surg. 2025 Dec;250:116646 doi: 10.1016/j.amjsurg.2025.116646.
Treatment of Intractable Cancer Pain with Resiniferatoxin - An Interim Study.
Mannes AJ, Heiss JD, Berger A, Alewine CC, Butman JA, Hughes MS, Rabbee N, Hayes C, Williams TS, Sapio MR, Iadarola MJ
NEJM Evid. 2025 Jun;4(6):EVIDoa2400423 doi: 10.1056/EVIDoa2400423.
Surgical Management of Gastroenteropancreatic Neuroendocrine Tumors.
Kenney LM, Hughes M
Cancers (Basel). 2025 Jan 23;17(3) doi: 10.3390/cancers17030377.
Integrative Multiomic Profiling of Triple-Negative Breast Cancer for Identifying Suitable Therapies.
Jovanović B, Church SE, Gorman KM, North K, Richardson ET 3rd, DiLullo M, Attaya V, Kasparian J, Mohammed-Abreu A, Kirkner G, Hughes ME, Lin NU, Mittendorf EA, Schnitt SJ, Tolaney SM, Goel S
Clin Cancer Res. 2024 Oct 15;30(20):4768-4779 doi: 10.1158/1078-0432.CCR-23-1242.
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