Dr. Chi-Fu Jeffrey Yang is a thoracic surgeon at Massachusetts General Hospital and an associate professor of surgery at Harvard Medical School. He practices all aspects of thoracic surgery, including procedures for conditions of the lung and mediastinum. He specializes in minimally invasive techniques. Dr. Yang has received numerous awards, including recognition for exceptional accomplishment in both clinical care and in teaching. In 2021, he received the Harvard Medical School Charles McCabe Faculty Prize for Excellence in Teaching. He is a member of the American Association for Thoracic Surgery and the Society of University Surgeons.
Dr. Yang leads several clinical studies. He is co-principal investigator and project leader of a $3.5 million NIH R01-funded study evaluating postoperative complications and recovery in cardiothoracic patients. He is also the co-principal investigator and project leader of a $1.5 million AHRQ R18-funded study evaluating lung cancer screening in Black women. Dr. Yang serves as Vice Chair of the Alliance Thoracic Surgery Group. Dr. Yang has been the lead or senior author on several high impact papers published in the British Medical Journal, Journal of Clinical Oncology, JAMA Oncology, Lancet Respiratory Medicine, Journal of Thoracic Oncology, Annals of Surgery, and Chest. He has written over 160 publications, including over 90 as first-, co-first or senior author. Dr. Yang is an editorial board member of the Journal of Thoracic and Cardiovascular Surgery, the Journal of Thoracic Diseases, and the Society of Thoracic Surgeons Online Curriculum. He is also an associate editor for Pearson’s General Thoracic Surgery.
Dr. Yang is focused on raising awareness of lung cancer screening. He started the American Lung Cancer Screening Initiative, a 501(c)(3) non-profit, which has worked with communities across 50 states to highlight the importance of lung screening. Since 2020, he has worked on resolutions, S. Res. 780, 462, 863, and 512 to raise awareness for lung cancer and lung cancer screening; these resolutions were passed in the U.S. Senate, by unanimous support from all 100 U.S. Senators. In 2021, he received the Harvard Medical School Dean's Community Service Faculty Award in recognition of his efforts.
When Dr. Yang is not at Mass General, he enjoys spending time with his wife, Phoebe, two daughters and his dog.
Selected publications from PubMed
AMPK-dependent maturation of hiPSC-derived cardiomyocytes induced by human cardiac fibroblast exosomes.
Qin K, Li X, Wu X, Xie X, Xiang K, Zhou H, Yang J, Fan C
Clin Exp Hypertens. 2026 Dec 31;48(1):2631601 doi: 10.1080/10641963.2026.2631601.
Laryngeal mask airway use during liver transplantation: perioperative outcomes in a propensity score-matched cohort.
Wu X, Dai T, Yang J, Yuan F, Chen Z, Li K, Gui D, Chen J, Xie S, Yang H, Lan L, He J, Wang G
Ann Med. 2026 Dec;58(1):2722412 doi: 10.1080/07853890.2026.2722412.
Diffusion and clearance of ropivacaine after serratus anterior plane block by CT imaging: a prospective, single-arm trial.
Yang XL, Wu G, Gao F, Yan TT, Wu XN, Gao W, Wang S, Wang S, Yang J
Ann Med. 2026 Dec;58(1):2707665 doi: 10.1080/07853890.2026.2707665.
Development and Validation of Nomograms to Predict Overall Survival and Cancer-Specific Survival for Non-Small Cell Lung Cancer with Chest Wall Invasion: A Retrospective Study Based on SEER Database.
Lu Q, Yang J, Yin H, You Z, Liu C, Hu Z, Xu Z
J Invest Surg. 2026 Dec;39(1):2611440 doi: 10.1080/08941939.2025.2611440.
Artificial intelligence-assisted proteomic signatures for discriminating malignant from benign pulmonary nodules.
Luo J, Dong Q, Yang J, Shan H, Zhong Q, Zhang Y, Wang G, Liu J, Yin Y
Transl Res. 2026 Oct;296:185-197 doi: 10.1016/j.trsl.2026.07.013.
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