Management/Team Work
Founder/CEO at Cortical Labs, Melbourne, Australia
Selected publications from PubMed
Engineering functional vasculatures to reconstruct sympathetic-parasympathetic circuits for bladder function after spinal cord injury.
Weng H, Xiao L, Li T, Chang H, Xie P, Zhu L, Zhang B, Lv S, Hu Z, Dai Y, Hoi PM, Liu W, Liu J, Rong L, Ren Y, He L
Bioact Mater. 2027 Jan;67:59-79 doi: 10.1016/j.bioactmat.2026.07.046.
Comparative efficacy and thyroid function effects of non-surgical treatments for benign thyroid nodules: a Bayesian network meta-analysis.
Weng H, Meng D, Liu G
Int J Hyperthermia. 2026 Dec;43(1):2713764 doi: 10.1080/02656736.2026.2713764.
Variable Selection in Ultra-high Dimensional Feature Space for the Cox Model with Interval-Censored Data.
Pak D, Zhang J, Wu D, Weng H, Li C
J Stat Plan Inference. 2026 Dec;245 pii: 106423. doi: 10.1016/j.jspi.2026.106423.
Isomucronulatol 7-O-glucoside attenuates post-AMI monocyte/macrophage cardiac recruitment via HIF-1α/THBS1-mediated immunometabolic adhesion.
Sun X, Wang H, Wan Y, Gu Y, Yang M, Chen T, Yi S, Qian Y, Yang Z, Zhang M, Ouyang Y, Weng H, Du Z, Wang W, Li C, Gao S
J Ethnopharmacol. 2026 Nov 15;370:121972 doi: 10.1016/j.jep.2026.121972.
Piezo2 inhibition enhances the survival and axonal regeneration of spinal motoneurons after brachial plexus avulsion.
Zhang Y, Sun F, Wo J, Yu L, Weng H, Huang Z, Li W, Jia B, He M, Li A, Zhou L
Neural Regen Res. 2026 Nov 1;21(11):5358-5368 doi: 10.4103/NRR.NRR-D-25-00991.
Despite in-vitro cortical neurons exhibiting similar electrophysiology as their counterparts in the brains of their original donor organisms, the question remains whether this electrical activity is analogous to the information processing and intelligence observed in the donor. The DishBrain project demonstrates that if given the right embodiment, structure, information landscape, and stimulus, in-vitro cortical neural networks can exhibit primitive information processing and intelligence. Through the use of high-density copper metal oxide semiconductor (CMOS) multi-electrode array (MEA) devices, a closed perception-action cycle loop can be achieved when coupled with the early video game of Pong. The MEA takes the electrical activity of the neurons and feeds it into a computer program as input. The outcome of the input in the virtual world is then fed back into the neurons and thus creating the closed loop. With neurons now exhibiting learning and information processing ability in an in-vitro setting, novel approaches to personalised medicine and the drug development affecting central nervous system (CNS) conditions are now possible.
Published
Dec 2022
Case: Human brain cells connect and transfer information through electrical signals, which then decide the movement of every part of our human body. However, once outside of the complex workings of the human body, could in-vitro brain cells on their own be capable of performing a similar function? Moreover, would they be able to improve their performance when feedback is provided? In the Puzzle X 2022 event, Hon Wang explains with a few slides, how their research firm Cortical Labs has cultivated in vitro human brain cells in a chip and connected them to a multi electronic array. In order to explore their abilities they wanted to see if they could teach them to play Pong (a very simple pac man era video game). This multi-electronic array works as a bridge for the electronic signals between the cells and the computer game simulation. They have performed many tests on in-vitro human cells, but during this public event they attempt the first live connection between the in-vitro cells (in Australia) and the game simulation PC (in Barcelona). It demonstrates how the cells interact with the multi electronic array and give indications of the paddle movement. The cells may not have a 100% rate of winning, but who does? How could this advancement in knowledge of the capabilities of human brain cells help in medicine? What could this wide open field in science mean for humanity? The future is yet uncertain but the speculations are really exciting!
Published
Nov 2022
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