François Pattou, 44 year old, is professor of Surgery in the Faculty of Medicine at the University of Lille 2, Lille, France. Head of the department of general and endocrine surgery at Lille University Hospital, he also leads a research group at the University of Lille 2, INSERM U859, devoted to the clinical development of biotherapies for treating diabetes. The recipient of more than 25 research grants from national and international institutions, including 7th Framework Program, Agence Nationale de la Recherche, OSEO, Juvenile Diabete Research Fundation, François Pattou has been awarded the Grand Prix of the National Academy of Medicine. He is author or co-author of more than 150 publications in peer reviewed journals such as New Engl J Med, Nature, J Clin Invest, Cell Metab or Gastroenterology (h-index 30, ISI Thompson / jan 2011). Regularly invited to give lectures on biotherapies for diabetes in international meetings, Francois Pattou is also the principal investigator of several ongoing clinical trials of islet cell transplantation in patients with severe type 1 diabetes and metabolic surgery in patients with type 2 diabetes.
Selected publications from PubMed
Immunometabolic endotypes define distinct clinical trajectories in type 2 diabetes.
Vuong BT, Delépine CM, Ratter-Rieck JM, Rinaldi E, Julla JB, Cussenot E, Diedisheim M, Raverdy V, Liu E, Fischer JS, Hepprich M, Alzaid F, Blériot C, Becht E, Cornuot C, de Keizer J, Abdelouahab MB, Chiral M, Pfeil R, Lipaeva P, Dörr D, Zaharia OP, Jolivet T, Alberge J, Potier C, Khider K, Oger F, Riveline JP, Vidal-Trecan T, Tubach F, Estellat C, Abecassis J, Silvin A, Hadjadj S, Varoquaux G, Wagner R, Froguel P, Bonnefond A, Saulnier PJ, Pattou F, Ginhoux F, Roden M, Trombetta M, Potier L, Herder C, Gautier JF, Donath MY, Bonadonna RC, Venteclef N
Cell Metab. 2026 Aug 25 pii: S1550-4131(26)00325-6. doi: 10.1016/j.cmet.2026.07.027.
New Obesity Definition and Clinical Obesity Prevalence for Global Metabolic Bariatric Surgery.
Cremona S, Cohen RV, Pattou F, Casajoana A, Sampaio Souza G, Raverdy V, Verkindt H, Blasio BTL, Roser P, Caiazzo R, Benaiges D, Zanata Petry TB, Rubino F
JAMA Netw Open. 2026 Aug 3;9(8):e2628395 doi: 10.1001/jamanetworkopen.2026.28395.
The circadian clock controls hepatic stellate cell activation via a BMAL1/CK1ε/REV-ERBα/transgelin signaling pathway.
Johanns M, Berthier A, Vandel J, Courquet S, Lapage M, Dubois-Chevalier J, Vinod M, Very N, Zummo FP, Bobowski-Gérard M, Toma G, Gheeraert C, Vertommen D, Herinckx G, Raverdy V, Pattou F, Staels B, Eeckhoute J, Lefebvre P
Proc Natl Acad Sci U S A. 2026 Jul 28;123(30):e2611767123 doi: 10.1073/pnas.2611767123.
Decision tree-based prediction of 5-year weight trajectories after bariatric surgery in adolescents and young adults: a retrospective cohort study from France and Sweden.
Gueorguieva I, Lespagnol C, Saux P, Jarvholm K, Stenberg E, Aubry E, Amsellem-Jager J, Coutant R, Dabbas M, Caiazzo R, Khen-Dunlop N, De Filippo G, Dagher I, Dubern B, Terraz C, Maggioni G, Preux P, Verkindt H, Oukhouya N, Olbers T, Pattou F
Int J Obes (Lond). 2026 Jul 1 doi: 10.1038/s41366-026-02134-y.
Minimally invasive pancreatectomy with mesentericoportal venous resection: Results from a French national cohort.
Karam E, de Ponthaud C, Nassar A, Pastier C, Castel A, Mazzotta A, Souche FR, Rhaiem R, Jolly E, Garnier J, Fara R, Viennet M, Giannone F, Gagnière J, Borie F, Boubaddi M, Schwarz L, Louis-Gaubert C, Pattou F, Meurisse N, Lubrano J, Valverde A, Pittau G, Doussot A, Ragot E, Bigourdan JM, Pinto A, Véziant J, Laurent A, El Amrani M, Girard E, Dembinski J, Bucur P, Addeo P, Charlaix AL, Lermite E, Paye F, Darnis B, Danion J, Birnbaum DJ, Jouffret L, Lupinacci RM, Brunaud L, Brunel M, Zemour J, Vece RR, Piardi T, David P, Le Bian AZ, Cunha AS, Corté H, Mahfouf S, Kianmanesh R, Muscari F, Sulpice L, Sauvanet A, Fuks D, Saint-Marc O, Dokmak S, Gaujoux S, AFC-2023 study group, Bertrand T, de Martino J, Rousseau G, Scatton O, Nepi A, David C, Marchese U, Naveendran G, Tzedakis S, Duval-Binet A, Santos Barreira Rodrigues SD, De Rosa R, Soubrane O, Barra M, Tribillon E, Fabre JM, Bardol T, Carrère N, Maulat C, Palen A, Ewald J, Turrini O, Leclerc J, Ayav A, Lequeu JB, Kuperas C, Facy O, Pessaux P, Kock A, Noirault M, Buc E, Aboukassem A, Bertrand M, Marichez A, Laurent C, Chiche L, Papet E, Pinson J, Monge M, Regenet N, Caiazzo R, Marcelle J, Vandermeulen M, De Roover A, Lacroix C, Bensignor T, Goasguen N, Pietrasz D, Accardo C, Turco C, Heyd B, Karoui M, Vix J, Gouader A, Gailleton R, Daskaliuk O, Piessen G, Bonnin E, Cherif R, Bianchi G, Zerbib P, Saudemont A, Truant S, Abba J, Chirica M, Léourier P, Regimbeau JM, Salamé E, Bachelier P, Bougard M, Deyrat J, Vuillermet C, Boullenois H, David M, Faure JP, Moutardier V, Scesa JL, Bouquot M, Khayat AI, Lazaar H, Thébault B, Le Roy B, Deheppe J, Sauvanet P, Thereaux J, Mayet A, Badic B, de Carbonnière A, Gugenheim J, Tresallet C, Chamakhi A, Chreim L, André M
HPB (Oxford). 2026 Jun 19 pii: S1365-182X(26)00662-3. doi: 10.1016/j.hpb.2026.06.006.
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