Alexander L. Vahrmeijer is currently doing research at Leiden University Medical Center. Vahrmeijer has a record of over 20 years of research. Received most influence from C.J.H. van de Velde. Vahrmeijer's main field of research is Indocyanine green, while research in Cancer surgery and Fluorescence-lifetime imaging microscopy have also been conducted.
Selected publications from PubMed
CEA-targeted fluorescence endoscopy for the detection of high-grade dysplasia and early invasive rectal cancer: A proof-of-concept trial.
Warmerdam MI, Dijkhuis TH, Linders DJG, Pesch CMW, Crobach ASLP, Matoshi A, Basiliya K, van den Berg SH, Cailler F, Peeters KCMJ, Holman FA, Mieog JSD, Vahrmeijer AL, Hilling DE, Boonstra JJ
Eur J Nucl Med Mol Imaging. 2026 Sep 3 doi: 10.1007/s00259-026-08155-z.
SPRAYDYE: a phase I/II randomised pilot study to assess the safety and feasibility of topically applied AKRO-6qcICG, a cathepsin-activatable fluorescent imaging agent, for real-time intraoperative resection margin assessment in breast-conserving surgery.
Pesch CMW, Linders DGJ, March TL, Pool M, Valentijn ARPM, Hilling DE, Walker E, Straight B, Mieog S, Liefers GJ, Cohen D, Hazelbag HM, Straver ME, Basilion JP, Rissmann R, Burggraaf J, Vahrmeijer AL
Front Surg. 2026;13:1845151 doi: 10.3389/fsurg.2026.1845151.
Real-Time Detection of Colorectal Cancer Using Topical Application of a pH-Activatable Fluorophore.
Linders DGJ, Ser J, Shamim M, Baibussunova A, Loggers JCJ, Noordam G, van den Burg D, van Acker GJD, Guicherit OR, Westerterp M, Kuppen PJK, Marinelli AWKS, Hilling DE, Peters EEM, Kashiwagi S, Henary M, Choi HS, Vahrmeijer AL
Mol Diagn Ther. 2026 Jul;30(4):689-706 doi: 10.1007/s40291-026-00853-6.
Assessing Intraoperative Tumor-to-Background Ratios Across Different Subsites of the Oral Cavity Using an Integrin-Specific Fluorescent Tracer.
Zweedijk BE, Osei-Agyeman MFAD, Lauwerends LJ, Robinson DJ, Abbasi H, de Gijsel JF, Mast H, Jonker BP, Hardillo JAU, Monserez DA, Sewnaik A, Baatenburg de Jong RJ, Verhoef C, Frangioni JV, Koppes SA, Hilling DE, Vahrmeijer AL, Keereweer S
Cancers (Basel). 2026 Jun 11;18(12) doi: 10.3390/cancers18121910.
Evaluating the utility of ICG-based NIR imaging for small intestine neuroendocrine tumors: Challenges and the need for tumor-specific tracers.
Dalmeijer SWR, Zweedijk BE, Boldewijn DF, Galema HA, van Ginhoven TM, Franssen GJH, van Velthuysen ML, Grünhagen DJ, Verhoef C, Vahrmeijer AL, Hilling DE, Keereweer S
Surg Oncol. 2026 Jun;66:102443 doi: 10.1016/j.suronc.2026.102443.
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